LEPTIN, RESISTIN AND OMENTIN BY PATIENTS WITH IMPAIRED GLUCOSE TOLERANCE AND DIABETES MELLITUS TYPE 2

Verbovoy Andrey Felixovich, Doctor of medical sciences, professor, head of sub-department of endocrinology, Samara State Medical University, diacenter@sama.ru
Solomonova Elena Sergeevna, Assistant, sub-department of endocrinology, Samara State Medical University, solomonova.el@yandex.ru
Pashentseva Anna Vladimirovna, Senior laboratorian, sub-department of endocrinology, Samara State Medical University, a-pashentseva@yandex.ru

612.018 – 074:611.018.26:616.379 – 008.64

101 patients with impaired glucose tolerance (IGT) aged 62,1 ± 1,2 years and 77 patients with type 2 diabetes mellitus (DM 2) aged 58,6 ± 1,04 years were included in this study. The control group contained 22 practically healthy patients (11 men and 11 women) of middle age 23,1 ± 1,0 years. Levels of glucose, lipid profile, insulin, leptin, resistin and omentin in blood were determined. Patients with IGT and DM 2 had atherogenic dislipidemia, hyperinsulinemia due to visceral obesity. Re-sistin level was increased in the examined patients both with IGT and DM 2. The patients with IGT and DM 2 had lower level of omentin and higher level of leptin in blood.

impaired glucose tolerance, type 2 diabetes mellitus, leptin, insulin, re-sistin, omentin.